Kalafo
Phekolo e ntlafalitsoeng ea Gut Microbiota
Mekhoa ea Phekolo ea Gut Microbiota:
1. Transplantation ea Microbiota:
Ho kenyelletsa ho fetisetsa gut microbiota ho tsoa ho motho ea phetseng hantle ho khutlisetsa botsitso ba maleng a moamoheli. Mokhoa ona o sebelisoa haholo-holo ho phekola mafu a ka mpeng a refractory, enteritis le lefu la mala a halefisang.
2. Phetoho ea Microbiota:
E kenyelletsa ho fetola sebopeho sa lijo, ho sebelisa li-probiotics kapa li-prebiotics, le mekhoa e meng ea ho lokisa sebopeho le ts'ebetso ea gut microbiota. Mokhoa ona o sebelisoa haholo-holo ho thibela le ho phekola mafu a kang intestinal dysbiosis le ho se sebetse ha 'mele oa ho itšireletsa mafung.
Phekolo ea Gut microbiota e bontšitse liphello tse tšepisang kalafo ea maloetse a fapa-fapaneng, haholo-holo tšimong ea mathata a amanang le mala le maemo a amanang le 'mele oa ho itšireletsa mafung. Patlisiso e tsoelang pele le boikoetliso ba bongaka lia hlokahala ho netefatsa ts'ebetso ea eona le ho rarolla mathata a amanang le tekheniki le polokeho.
Ho kenella ha Gut Microbiota - Mokhoa o Mocha oa ho Phekola Autism:
Autism, lefu la neurodevelopmental le khetholloang ke mathata a ho sebelisana le batho, puisano ea lipuo, le ho pheta-pheta boitšoaro, e amahanngoa le bophelo bo botle ba mala. Ka ho lokisa gut microbiota le ho ntlafatsa bophelo bo botle ba mala, litlamorao tse ntle ho matšoao a autism li ka fihlelleha. Sengoliloeng sena se hlahloba katleho ea bophelo bo botle ba mala ho phekola autism.
Kamano lipakeng tsa Gut Health le Autism:
Batho ba nang le autism ba atisa ho ba le mathata a mala a kang letšollo, pipitlelano le mathata a tšilo ea lijo. Lipatlisiso li senotse liphapang tse teng ka har'a gut microbiota ea batho ba nang le autism ha ba bapisoa le ba se nang eona. Ho se leka-lekane ha microbiota ho ka senya ts'ebetso ea thibelo ea mala, ho baka likarabo tsa ho ruruha tse amang nts'etsopele le ts'ebetso ea tsamaiso ea methapo. Ka hona, ho ntlafatsa bophelo bo botle ba mala ho hlahile e le mokhoa o mocha oa ho phekola autism.
Mokhatlo oa Probiotics le Autism:
Li-probiotics, likokoana-hloko tse molemo tse khothalletsang bophelo bo botle ba mala, li bapala karolo ea bohlokoa ho laola tekano ea microbiota ea mala, ho ntlafatsa ts'ebetso ea tšitiso ea mala, le ho fokotsa ho ruruha. Liphuputso li bontšitse hore tšebeliso ea li-probiotics e ka ntlafatsa mathata a mala ho batho ba nang le autism, ea susumetsa boitšoaro ba bona le likamano tsa sechaba. Ka mohlala, phuputso e 'ngoe e fumane hore tsamaiso ea molomo ea li-probiotics e lebisitse ho ntlafatso ea boitšoaro ba sechaba le puo ea puo ho batho ba nang le autism.
Li-probiotics ke metsoalle e metle bakeng sa batho
Kamano lipakeng tsa Gut Microbiota le ho ruruha ha boko:
Gut microbiota e bapala karolo ea bohlokoa ho bolokeng bophelo bo botle ba motho ka kakaretso, ho thusa tšilong ea lijo, le ho hlahisa limatlafatsi tsa bohlokoa. Ho feta moo, e susumetsa sesole sa 'mele mme e hlahisa lik'hemik'hale tse amang ts'ebetso ea boko. Ho se leka-lekane ha gut microbiota ho ka baka mafu.
Ntle le moo, gut microbiota le eona e ka ama bophelo bo botle ba boko. Lipatlisiso li bonts'a hore boko le gut microbiota li hokahane ka axis ea boko ba mala. The gut-brain axis ke marang-rang a rarahaneng a entsoeng ka li-neurone, liprotheine le lintho tsa lik'hemik'hale tse thusang puisano pakeng tsa tsamaiso ea lijo le boko.
Kamano lipakeng tsa gut microbiota le lefu la Alzheimer e bohlokoa haholo. Gut microbiota e ka laola nts'etsopele ea methapo ea kutlo ka "microbiota-gut-brain axis". Ha gut microbiota e senyeha, e ka lebisa ho mathata a fapaneng a metabolism tsamaisong ea methapo, joalo ka lefu la Alzheimer's. Ho se leka-lekane ka har'a gut microbiota ho ka baka tšitiso ea tsamaiso ea methapo e bohareng le ho ruruha ho sa feleng, ho etsa hore ho behoe protheine e kholo ea pathogenic lefung la Alzheimer le tsejoang e le beta-amyloid (Aβ). Ho se leka-lekane ha li-neurotransmitter le khatello ea oxidative ho ka mpefatsa tsoelo-pele ea lefu la Alzheimer's.
Haeba khopolo-taba ena e tiisitsoe, lipakane tse ka 'nang tsa e-ba teng bakeng sa thibelo le phekolo ea lefu la Alzheimer li ka kenyelletsa li-prebiotics, probiotics, transplantation ea mantle, lithibela-mafu, le mekhoa e khethehileng ea lijo. Phekolo ea Gut microbiota e ikemiselitse ho bopa bocha micobiota ea mala ka ho sebetsa ho microbiota-gut-brain axis. Mokhoa ona o batla ho fokotsa li-byproducts tse sa tloaelehang tsa metabolic, ho fokotsa ho kenella ha lisele tsa 'mele tsa ho itšireletsa mafung ka bokong, ho fokotsa ho ruruha ha methapo, ka lebaka leo, ho thibela ho bokellana ha Aβ, ho khothalletsa ho bokellana ha li-plaque tsa Aβ. Gut microbiota therapy, ka hona, ka mokhoa o hlophisehileng e bapala karolo ea ho sebetsana le lefu la Alzheimer's.